Antifungal Activity and Toxicity of Two New types of Polyene Antibiotics against Four Species of Rice Pathogenic Fungi

查看全文 作　　者：Hui [1]LU;Meiping [2]WEN;Saijin [1]WEI;Xiaorong [1]TU;Jia [1]XU;Guoquan [1]TU

机构地区：[1]College of Biological Science and Engineering,Jiangxi Agricultural University;[2]Affiliated Hospital of Jiangxi Agricultural University

出　　处：《Plant Diseases and Pests》索引2012年第3卷第3期,共4页

基　　金：Supported by National Natural Science Foundation of China(30960011 and 31071724); Natural Science Foundation of Jiangxi Province (2009GZN0030);Science and Technology Support Program of Jiangxi Province(2007BN14002) 摘　　要：The antifungal activity and toxicity of new type polyene macrolide antibiotics-Antifungalmycin 702 and Fungichromin against Rhizoctonia solani,Helminthosporium sigmoideum Cav. ,Magnaporthe grisea and Ustilaginoidea virens were studied by mycelial growth rate method and mycelial dry weight method in vitro. The results showed that both of Antifungalmycin 702 and Fungichromin had strong antifungal activity against four speices of rice pathogenic fungi. Treated with 50 μg / mL Antifungalmycin 702 ,the inhibitory rates of Antifungalmycin 702 against R. solani,H. sigmoideum Cav. ,M. grisea and U. virens were 100% 、 100% 、91. 20% and 68. 10% ,and EC 50 and EC 90 were 7. 00,10. 30,14. 41,26. 71 and 13. 20,17. 66,27. 67,128. 28 μg / mL,respectively. Treated with 13 μg / mL Fungichromin,the inhibitory rates of Fungichromin against four speices of rice pathogenic fungi were 78. 20% ,100% ,100% and 79. 17% ,and EC 50 and EC 90 were 1. 47,1. 91,2. 37,0. 20 and 41. 05,3. 92,4. 34,135. 54 μg / mL,respectively. The antifungal activity of Fungichromin was stronger than Antifungalmycin 702. 关键词：大环内酯类抗生素水稻纹枯病菌病原真菌抑菌活性毒性多烯抗真菌活性生长速率法

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Antifungal Activity and Toxicity of Two New types of Polyene Antibiotics against Four Species of Rice Pathogenic Fungi

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