Two single nucleotide polymorphisms in the GDF5 gene are associated with development dysplasia of the hip in Chinese female population

查看全文 作　　者：ZHAO [1,2]LiXi;PAN [1,2]Hong;WANG [1,2]Jing;CHENG [1,2]Zhi;CHENG [1,2]LongFei;WANG [1,2]BinBin;MA [1,2,3]Xu

机构地区：[1]Graduate School of Peking Union Medical College;[2]National Research Institute for Family Planning;[3]World Health Organization Collaborating Centre for Research in Human Reproduction

出　　处：《Science China(Life Sciences)》索引2013年第56卷第11期,共3页

基　　金：supported by the National Basic Research Program of China(2010CB529500);the International Cooperative Research Program of Translational Medicine for Congenital Heart Defects,and Ministry of Science and Technology of China(2011DFA33120) 摘　　要：Development dysplasia of the hip(DDH)is one of the most common hip defects in newborns.The main phenotypes of the disease are partial or whole femoral head extrusion from the acetabulum[1].Because the frequency of DDH in monozygotic twins was higher than that in dizygotic twins,and the affected individuals were often in the same family[2],we are focusing on the genetic factor in the present study. 关键词：发育不良单核苷酸多态性髋关节人口女性中国基因遗传因素

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Two single nucleotide polymorphisms in the GDF5 gene are associated with development dysplasia of the hip in Chinese female population

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