Hypercoagulability in cancer patients grouped by syndromes differentiated with the theory of abnormal hilit in traditional Uyghur medicine

查看全文 作　　者：Yin [1,2]Chen;[3]Halmurat.Upur;Meizuo [1]Zhong;[3]Renaguli.Aizezi 机构地区：[1]Department of Oncology,Xiangya Hospital,Central South University;[2]Department of Oncology,the Fourth Affiliated Hospital of Xinjiang Medical University;[3]Xinjiang Medical University 出　　处：《Journal of Traditional Chinese Medicine》索引2014年第34卷第1期,共4页 基　　金：Supported by the Special Program for Key Basic Research of the Ministry of Science and Technology,China(No.2011CB512004) 摘　　要：OBJECTIVE:To investigate the relationship in malignant-neoplasm patients of hypercoagulability between syndromes differentiated with the theory of abnormal hilit in traditional Uyghur medicine(TUM).METHODS:A total of 248 patients with malignant tumors were enrolled.Based on the theory of TUM they were divided into two groups:abnormal Savda and abnormal Non-Savda(including abnormal Khan,abnormal Sepra and abnormal Belghem types);fifty healthy volunteers were selected as controls.Platelet(PLT),prothrombin time(PT),plasma fibrinogen(FIB),thrombin time(TT),activated partial thromboplastin time(aPTT)and D-Dimer(D-D)were measured in both groups.RESULTS:Compared with the control and abnor-mal Non-Savda groups,in the abnormal Savda group the PLT count increased(P<0.05),the PT was lengthened(P<0.01),and the FIB significantly increased(P<0.01).D-Ds in the three groups were significantly different(P<0.05).No significant difference was found inTT and aPTT values(P>0.05).CONCLUSION:Hypercoagulability existed in patients with malignant tumors in the different types of TUM syndromes,especially in the abnormal Savda group;this was characterized by increased blood viscosity,platelet aggregation and thrombosis.D-D appears to be a significant predictor for the therapeutic effect of TUM in relation to malignant tumor therapies. 关 键 词：肿瘤患者 传统医药 维吾尔族 综合征 异常 状态 体液 鉴别