Traditional Chinese Medicine for Diminished Ovarian Reserve: A Systematic Review and Meta-analysis

查看全文 作　　者：Tian [1]Xia;Rui-hong [1]Ma;Wei [2]Mu;Meng-di [1]Hu;Sai-hua [1]Ma;Shu-wen [1]Mao;Yu [1]Fu

机构地区：[1]Collaborative Innovation Center of Integrated Traditional and Western Medicine for Reproductive Health, The First Affiliated Hospital, Tianjin University of Traditional Chinese Medicine;[2]Center for Evidence-Based Medicine, Tianjin University of Traditional Chinese Medicine

出　　处：《Chinese Herbal Medicines》索引2014年第6卷第2期,共10页

基　　金：National Natural Science Foundation of China(81273791) 摘　　要：Objective To assess the effectiveness and safety of traditional Chinese medicine(TCM)for women with diminished ovarian reserve(DOR).Methods A literature search was conducted in eight electronic databases for randomized controlled trials.Results Seventeen randomized controlled trials involving 1174 patients were included.Meta-analysis indicated that TCM was superior to Western medicine(WM)in reducing basal serum FSH level[MD=-1.70,95%CI(-2.63,-0.77);P=0.0004]and FSH/LH(MD=-0.43,95%CI[-0.56,-0.30];P=0.0001),and the effect was more obvious two months after the last treatment(MD=-4.60,95%CI[-6.26,-2.90],P<0.000 01 and MD=-0.56,95%CI[-0.85,-0.28],P=0.0001),and increasing antral follicle count(AFC)(MD=0.44,95%CI[0.04-0.83];P=0.03).The review also revealed the positive role of CMM as an adjuvant to IVF-ET in improving pregnancy rate(PR=1.75,95%CI[1.25,2.46];P=0.001).Conclusion TCM,with its unique way of replenishing the kidney,may provide an effective and safe alternative therapy to patients with DOR. 关键词：中国传统医学 Meta分析储备卵巢随机对照试验评价系统 IVF-ET

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Traditional Chinese Medicine for Diminished Ovarian Reserve: A Systematic Review and Meta-analysis

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