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Comparison of clinical effectiveness of acupuncture and a Western drug on allergic rhinitis:study protocol for a randomized controlled trial

查看全文 作  者:Yanping [1]Wang;Sheng [2]Chen;Peng [2]Wang;Cheng [2]Tan;Chang [3]Zhang;Zhihong [2]Shi;Jiping [2]Zhao 高影响力作者 机构地区:[1]School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine;[2]Department of Acupuncture and Moxibustion, Dong-zhimen Hospital Affiliated to Beijing University of Chinese Medicine;[3]Chinese Medicine Department, Central Hospital of China Aerospace Corporation of Peking University高影响力机构 出  处:《Journal of Traditional Chinese Medicine》索引2014年第34卷第3期,共7页高影响力期刊 基  金:Supported by Capital Research on the Clinical Characteristic Application Projects,Beijing Municipal Science & Technology Commission(No.D101100050010022) 摘  要:OBJECTIVE: To compare the efficacy of an acupuncture regimen for persistent allergic rhinitis(PER), aimed at improving a patient's mind or Shen in Traditional Chinese Medicine, to that of a second-generation H1-receptor antagonist, cetirizine hydrochloride.METHODS: This multicenter, randomized, controlled clinical trial on PER will be conducted at three institutions in China. The total study period will be 9 weeks. After a 1-week preparatory screening period, 240 eligible participants with PER willbe randomized to receive acupuncture or pharmacotherapy(1∶1) for 4 weeks with a 4-week follow-up. The primary outcome will be changes in7-day average total nasal symptom score. Secondary outcome measures include rhinoconjunctivitis quality of life questionnaire score and total non-nasal symptom score.RESULTS:The presence and seriousness of psychological and emotional impairments should be considered in therapeutic programs for allergic rhinitis.No clinical trial for treating allergic rhinitis via acupuncture regulation of psychological and emotionalactivitieshasbeenreported.CONCLUSION:The findings of the trial will allow us to determine the effects of the mind(Shen)-regulation treatment approach. We will also be able to confirm if the effects of acupuncture are equivalent to those of the conventional drug cetirizine hydrochloride. 关 键 词:随机对照试验 过敏性鼻炎 临床疗效 针灸 中国传统医学 盐酸西替利嗪 西药 联合治疗
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