The Possibility and Molecular Mechanisms of Cell Pyroptosis After Cerebral Ischemia

查看全文 作　　者：Zhaofei [1]Dong;Kuang [1]Pan;Jingrui [1]Pan;Qingxia [1]Peng;Yidong [1,2,3]Wang

机构地区：[1]Department of Neurology, Sun Yat-sen Memorial Hospital,Sun Yat-sen University;[2]Guangdong Province Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-sen University;[3]Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University

出　　处：《Neuroscience Bulletin》索引2018年第34卷第6期,共6页

基　　金：supported by the Natural Science Foundation of Guangdong Province, China (2017A030313869);the Science and Technology Project of Guangzhou City, China (201607010325) 摘　　要：Introduction Stroke is an important disease that is prevalent worldwide [1-3].Ischemic stroke accounts for 80%of stroke cases. Currently,evidence-based effective treatments for ischemic stroke are limited,and only intravenous throm- bolysis with Alteplase (a commercially available throm- bolytic agent)within 4.5 h of stroke onset and thrombectomy and arterial thrombolysis within 6-24h of onset are effective [4,5].However,because these two treatments have strict indications and certain risks (reper- fusion injury and bleeding)[5-8],there is an urgent need to develop new treatment methods.Thus,comprehensive elucidation of the molecular mechanisms underlying ischemic brain damage and the search for key signaling pathways and protein molecules are important for guiding the clinical treatment of ischemic stroke. 关键词：The Possibility and Molecular Mechanisms of Cell Pyroptosis After Cerebral Ischemia ASC

相关文献

参考文献（58）
引证文献（26）
耦合文献（1516）

参考文献(58)

引证文献(26)

耦合文献(1516)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

The Possibility and Molecular Mechanisms of Cell Pyroptosis After Cerebral Ischemia

参考文献(58)

引证文献(26)

耦合文献(1516)

用户提示