Micro/-nanoscaled topography-coupled-mechanical action into functional biointerface

查看全文 作　　者：Quanmei [1]Sun;Zhuo [1]Ao;Jiantao [1]Feng;Hongyi [1,2]Li;Dong [1]Han

机构地区：[1]National Center for Nanoscience and Technology;[2]Cardiology Division, Beijing Hospital of the Ministry of Health

出　　处：《Chinese Science Bulletin》索引2014年第59卷第28期,共7页

基　　金：supported by the project of 973 in Ministry of Science and Technology of China(2012CB933800);the Key Research Program of the Chinese Academy of Sciences(KJZD-EW-M01) 摘　　要：The micro/-nanoscaled functional biointerfaces aroused much interest of their key unit element to present unique functions. So far it is still difficult to describe the whole picture of this process. More and more evidences are beginning to support the theory of ‘‘mirco/-nanotopography-coupled-mechanical(TCM) action'' into functional biointerfaces.Herein, we aim to highlight TCM action on varied micro/-nanoscaled functional biointerfaces, namely to achieve better understanding of micro/-nanoscaled structures by introducing interfacial mechanical behaviors. In this article, recent progressions on ‘‘TCM on air/liquid/solid-phase biointerfaces in nature'', ‘‘in vivo TCM behaviors at micro/-nanoscales' ',‘‘TCM in micro/-nanoscaled artificial surface with living Cells' ' and ‘‘topography, interfacial curvature, mechanics' 'are reviewed. Certain new concepts of ‘‘TCM action based on spatial curvature'', ‘‘medically functional biointerfaces' ' and‘‘biomechanopharmacology'' are also proposed. 关键词：机械地形界面力学行为生物界面动作耦合界面功能 TCM

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Micro/-nanoscaled topography-coupled-mechanical action into functional biointerface

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