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Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology

查看全文 作  者:SU Chun-[1,2]Yan;MING Qian-[3]Liang;RAHMAN [4]Khalid;HAN [1]Ting;QIN Lu-[1]Ping 高影响力作者 机构地区:[1]Department of Pharmacognosy, School of Pharmacy, Second Military Medical University;[2]Institute of Medicinal Plant Development, Chinese Academy of Medical Science and Peking Union Medical College;[3]Department of Pharmacognosy, School of Pharmacy, Third Military Medical University;[4]Faculty of Science, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University高影响力机构 出  处:《Chinese Journal of Natural Medicines》索引2015年第13卷第3期,共20页高影响力期刊 基  金:supported by the Young Scientist Special Project of the National High Technology Research and Development Program of China(No.2014AA020508);National Nature Science Foundation of China(No.81473301) 摘  要:Salvia miltiorrhiza Bunge(SM) is a very popular medicinal plant that has been extensively applied for many years to treat various diseases, especially coronary heart diseases and cerebrovascular diseases, either alone or in combination with other Chinese plant-based medicines. Although a large number of studies on SM have been performed, they are scattered across a variety of publications. The present review is an up-to-date summary of the published scientific information about the traditional uses, chemical constituents, pharmacological effects, side effects, and drug interactions with SM, in order to lay the foundation for further investigations and better utilization of SM. SM contains diverse chemical components including diterpenoid quinones, hydrophilic phenolic acids, and essential oils. Many pharmacological studies have been done on SM during the last 30 years, focusing on the cardiovascular and cerebrovascular effects, and the antioxidative, neuroprotective, antifibrotic, anti-inflammatory, and antineoplastic activities. The research results strongly support the notion that SM has beneficial therapeutic properties and has a potential of being an effective adaptogenic remedy. 关 键 词:丹参 心血管疾病 抗癌抗菌素 影响 复习
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