Case of plasmablastic lymphoma of the sigmoid colon and literature review

查看全文 作　　者：Tomoko [1]Haramura;Masashi [1]Haraguchi;Junji [2]Irie;Shinichiro [1]Ito;Hirotaka [1]Tokai;Kazumasa [1]Noda;Masachika [1]Kitajima;Shigeki [1]Minami;Keiji [1]Inoue;Yuya [3]Sasaki;Koichi [3]Oshima;Susumu [4]Eguchi

机构地区：[1]Department of Surgery, Nagasaki Harbor Medical Center City Hospital;[2]Department of Pathology, Nagasaki Harbor Medical Center City Hospital;[3]Department of Pathology, Kurume University;[4]Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences

出　　处：《World Journal of Gastroenterology》索引2015年第21卷第24期,共6页

摘　　要：Plasmablastic lymphoma(PBL) is a rare form of nonHodgkin's lymphoma that is associated with human immunodeficiency virus(HIV) infection. Although PBL is most commonly observed in the oral cavity of HIV-positive patients, it can also be observed at extra-oral sites in HIV-negative patients. This report represents an unusual case of HIV-negative PBL that occurred in the sigmoid colon. This patient had a history of systemic lupus erythematosus and an underlying immunosuppressive state from long term steroid therapy. The lymphoma cells were positive for CD138, kappa light chain restriction and Epstein-Barr virus and negative for CD20/L26, CD3, CD79 a, UCHL1(CD45RO) and cytokeratin(AE1/AE3). The patient died approximately 2 mo after the operation. In the present paper, we review cases of PBL of the colon in HIVnegative patients. 关键词：Plasmablastic LYMPHOMA SIGMOID COLON Humanimmunodeficiency virus-negative IMMUNOSUPPRESSIVE state Extra-oral site

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Case of plasmablastic lymphoma of the sigmoid colon and literature review

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