Structure and antibacterial property of a new diterpenoid from Euphorbia helioscopia

查看全文 作　　者：GENG [1]Di;YI Li-[1]Tao;SHI [2]Yao;MIN Zhi-[2]Da

机构地区：[1]College of Chemical Engineering, Huaqiao University;[2]Department of Natural Medicinal Chemistry, China Pharmaceutical University

出　　处：《Chinese Journal of Natural Medicines》索引2015年第13卷第9期,共3页

基　　金：supported by the Fundamental Research Funds for the Central Universities(No.JB-ZR1226);the National Natural Science Foundation of China(No.81202940) 摘　　要：The present study was designed to isolate and evaluate the antibacterial activity of the compounds from the whole plant of Euphorbia helioscopia L.. Various chromatographic techniques were used to isolate and purify the compound. The structure of the compound was elucidated on basis of spectral data(1H NMR, 13 C NMR, 1H-1H COSY, HSQC, HMBC, NOESY, IR, and HR-ESI-MS). A new jatrophone-type diterpenoid(14α,15β-diacetoxy-3β-benzoyloxy-7β-nicotinoyloxy-9-oxo-jatropha-5E,11E-diene), named euphoheliosnoid E(1), was isolated from the whole plant of E. helioscopia L. Compound 1 showed significant anti-microbial activity against oral pathogens. 关键词：药学药剂学调剂学剂型

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Structure and antibacterial property of a new diterpenoid from Euphorbia helioscopia

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