Poly(ADP-ribosyl)ation of Apoptosis Antagonizing Transcription Factor Involved in Hydroquinone-Induced DNA Damage Response

查看全文 作　　者：ling xiao [1,2]xuan;liu jia [1]xian;yun [1]lin;du yu [3]jun;chen shao [4]qian;chen jia [5]long;tang huan [1]wen;liu lin [1]hua

机构地区：[1]Department of Environmental and Occupational Health,Dongguan Key Laboratory of Environmental Medicine,School of Public Health,Guangdong Medical University,Dongguan 523808,Guangdong,China;[2]School of Public Health,Guangzhou Medical University,Guangzhou 510182,Guangdong,China;[3]Electrocardiogram Department of Cardiovascular Center,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524023,Guangdong,China;[4]Department of Clinical Laboratory,The First Afiliated Hospital of Sun Yat-sen University,Guangzhou 510080,Guangdong,China;[5]Department of Occupational Health and Occupational Medicine,Guangdong Provincial Key Laboratory of Tropical Disease Research,school of Public Health and Tropical Medicine,Southern Medical University,Guangzhou 510515,Guangdong,China

出　　处：《Biomedical and Environmental Sciences》索引2016年第29卷第1期,共5页

基　　金：supported by grants from the National Natural Science Foundation of China(81202231;81273116;81430079);the Science and Technology Program of Guangdong Bureau of Science and Technology;China(2013B021800069) 摘　　要：The molecular mechanism of DNA damage induced by hydroquinone(HQ)remains unclear.Poly(ADP-ribose)polymerase-1(PARP-1)usually works as a DNA damage sensor,and hence,it is possible that PARP-1 is involved in the DNA damage response induced by HQ.In TK6 cells treated with HQ,PARP activity as well as the expression of apoptosis antagonizing 关键词：DNA损伤反应过程转录因子抗凋亡诱导氢醌糖基多聚

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Poly(ADP-ribosyl)ation of Apoptosis Antagonizing Transcription Factor Involved in Hydroquinone-Induced DNA Damage Response

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