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Amniotic fluid: Source of trophic factors for the developingintestine

查看全文 作  者:Soham [1]Dasgupta;Shreyas [1,2]Arya;Sanjeev [3]Choudhary;Sunil K [14]Jain 高影响力作者 机构地区:[1]Department of Pediatrics,University of Texas Medical Branch,Galveston,TX 77555,United States,2Department of Endocrinology,University of Texas Medical Branch,Galveston,TX 77555,United States;[3]Department of Internal Medicine,University of Texas Medical Branch,Galveston,TX 77555,United States;[4]Department of Neonatology,University of Texas Medical Branch,Galveston,TX 77555,United States高影响力机构 出  处:《World Journal of Gastrointestinal Pathophysiology》索引2016年第7卷第1期,共10页高影响力期刊 摘  要:The gastrointestinal tract(GIT) is a complex system, which changes in response to requirements of the body. GIT represents a barrier to the external environment. To achieve this, epithelial cells must renew rapidly. This renewal of epithelial cells starts in the fetal life under the influence of many GIT peptides by swallowing amniotic fluid(AF). Development and maturation of GIT is a very complex cascade that begins long before birth and continues during infancy and childhood by breastfeeding. Many factors like genetic preprogramming, local and systemic endocrine secretions and many trophic factors(TF) from swallowed AF contribute and modulate the development and growth of the GIT. GIT morphogenesis, differentiation and functional development depend on the activity of various TF in the AF. This manuscript will review the role of AF borne TF in the development of GIT. 关 键 词:Amniotic FLUID GASTROINTESTINAL FACTORS TRACT TROPHIC Development
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