Direct reprogramming of somatic cells into neural stem cells or neurons for neurological disorders

查看全文 作　　者：Shaoping [1]Hou;Paul [2,3]Lu

机构地区：[1]Spinal Cord Research Center, Department of Neurobiology & Anatomy, Drexel University College of Medicine, Philadelphia, PA, USA;[2]Veterans Administration Medical Center, San Diego, CA, USA;[3]Department of Neurosciences, University of California at San Diego, La Jolla, CA, USA

出　　处：《Neural Regeneration Research》索引2016年第11卷第1期,共4页

基　　金：supported by the Veterans Administration;the Craig H.Neilsen Foundation(280072 to SH);the California Institute for Regenerative Medicine 摘　　要：Direct reprogramming of somatic cells into neurons or neural stem cells is one of the most important frontier fields in current neuroscience research. Without undergoing the pluripotency stage, induced neurons or induced neural stem cells are a safer and timelier manner resource in comparison to those derived from induced pluripotent stem cells. In this prospective, we review the recent advances in generation of induced neurons and induced neural stem cells in vitro and in vivo and their potential treatments of neurological disorders. 关键词：神经干细胞神经系统疾病神经细胞重编程体细胞多能干细胞神经元科学研究

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Direct reprogramming of somatic cells into neural stem cells or neurons for neurological disorders

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