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Viral-mediated gene therapy for spinal cord injury(SCI) from a translational neuroanatomical perspective

查看全文 作  者:Andrew P [1,2]Tosolini;Renée [1,2]Morris 高影响力作者 机构地区:[1]Translational Neuroscience Facility, School of Medical Sciences, the University of New South Wales (UNSW Australia), Sydney, Australia;[2]Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, UK高影响力机构 出  处:《Neural Regeneration Research》索引2016年第11卷第5期,共2页高影响力期刊 基  金:supported by grants from the National Health and Medical Research Council(NHMRC)of Australia;the Brain Foundation of Australia awarded to RM 摘  要:Repairing spinal cord injury(SCI)is one of the most challenging endeavours currently faced by neuroscientists.One promising therapeutic avenue to reverse this once considered permanent condition is gene therapy,however progress has been hampered by the anatomica intricacy of the spinal cord itself as well as by the sheer complexity of the molecular cascades of events that take place in the injured cord. 关 键 词:神经解剖学 脊髓损伤 基因治疗 SCI 平移 介导 病毒 复杂性
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