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The revised Atlanta criteria 2012 altered the classification,severity assessment and management of acute pancreatitis

查看全文 作　　者：Jie [1]Huang;Hong-Ping [1]Qu;Yun-Feng [2]Zheng;Xu-Wei [3]Song;Lei [1]Li;Zhi-Wei [3]Xu;En-Qiang [4]Mao;Er-Zhen [1]Chen 高影响力作者 机构地区：[1]Department of Intensive Care Unit Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China;[2]Department of Radiology Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China;[3]Department of Surgery Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China;[4]Department of Emergency Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China高影响力机构 出　　处：《Hepatobiliary & Pancreatic Diseases International》索引2016年第15卷第3期,共6页高影响力期刊 基　　金：supported by a grant from Shanghai Science and Technology Committee(12411950500) 摘　　要：BACKGROUND:The Atlanta criteria for acute pancreatitis(AP) has been revised recently.This study was to evaluate its practical value in classification of AP,the severity assessment and management.METHODS:The clinical features,severity classification,outcome and risk factors for mortality of 3212 AP patients who had been admitted in Ruijin Hospital from 2004 to 2011 were analyzed based on the revised Atlanta criteria(RAC) and the original Atlanta criteria(OAC).RESULTS:Compared to the OAC group,the incidence of severe acute pancreatitis(SAP) was decreased by approximately one half(13.9% vs 28.2%) in the RAC group.The RAC presented a lower sensitivity but higher specificity,and its predictive value for severity and poor outcome was higher than those of the OAC.The proportion of SAP diagnosis and ICU admission in the early phase in the RAC group was significantly lower than that in the OAC group(P<0.05).Based on the RAC,the risk factors for death among SAP patients were older age,high CT severity index(CTSI),renal failure,cardiovascular failure,acute necrotic collection and walled-off necrosis.Compared to the OAC,the acute physiology and chronic health evaluation II(APACHE II) score,Ranson score,idiopathic etiology,respiratory failure and laparotomy debridement were not risk factors of death in contrast to walled-off necrosis.Interestingly,hypertriglyceridemia-related SAP had good outcomes in both groups.CONCLUSIONS:The RAC showed a higher predictive value for severity and poorer outcome than the OAC.However,the RAC resulted in fewer ICU admissions in the early phase due to its lower sensitivity for diagnosis of SAP.Among SAP cases,older age,high CTSI,renal and cardiovascular failure,complications of acute necrotic collection and walled-off necrosis were independent risk factors for mortality. 关 键 词：急性胰腺炎 亚特兰大 标准分析 严重程度 分类 管理 评估 SED
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