Highly pathogenic avian influenza H5N1 Clade 2.3.2.1c virus in migratory birds,2014–2015

查看全文 作　　者：Yuhai [1,3,6]Bi;Jianjun [2,7]Chen;Zhenjie [4]Zhang;Mingxin [2]Li;Tianlong [5]Cai;Kirill [7]Sharshov;Ivan [7]Susloparov;Alexander [7]Shestopalov;Gary [3]Wong;Yubang [8]He;Zhi [8]Xing;Jianqing [8]Sun;Di [3]Liu;Yingxia [1]Liu;Lei [1]Liu;Wenjun [3,6]Liu;Fumin [5,6]Lei;Weifeng [4]Shi;George F. [1,3,6,9]Gao

机构地区：[1]Shenzhen Key Laboratory of Pathogen and Immunity,State Key Discipline of Infectious Disease,Shenzhen Third People's Hospital,Shenzhen 518112,China;[2]CAS Key Laboratory of Special Pathogens and Biosafety,Wuhan Institute of Virology Chinese Academy of Sciences,Wuhan 430071,China;[3]CAS Key Laboratory of Pathogenic Microbiology and Immunology(CASPMI),Institute of Microbiology,Chinese Academy of Sciences,Beijing 100101,China;[4]Institute of Pathogen Biology,Taishan Medical College,Taishan 271000,China;[5]CAS Key Laboratory of Zoological Systematics and Evolution,Institute of Zoology,Chinese Academy of Sciences,Beijing 100101,China;[6]Center for Influenza Research and Early-warning(CASCIRE),Chinese Academy of Sciences,Beijing 100101,China;[7]Research Institute of Experimental and Clinical Medicine,Novosibirsk State University,Novosibirsk 630090,Russia;[8]Qinghai Lake National Nature Reserve,State Forestry Administration,Xining 810007,China;[9]Office of Director-General,Chinese Center for Disease Control and Prevention(China CDC),and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease,Zhejiang University,Hangzhou 310058,China

出　　处：《Virologica Sinica》索引2016年第31卷第4期,共6页

基　　金：supported by grants from the National Natural Science Foundation of China (31311120063,81470096,31570026,31471253);the Ministry of Education and Science of the Russian Federation (Chinese-Russian project:RFMEFI61315X0045);the intramural special grant for influenza virus research from the Chinese Academy of Sciences (KJZD-EW-L09);the IDRCAPEIR program (106915-001);Special Project of Ministry of Science and Technology (2013FY113500);supported by the “Taishan Scholar” project of Shandong Province 摘　　要：A novel Clade 2.3.2.1c H5N1 reassortant virus caused several outbreaks in wild birds in some regions of China from late 2014 to 2015.Based on the genetic and phylogenetic analyses,the viruses possess a stable gene constellation with a Clade 2.3.2.1c HA,a H9N2-derived PB2 gene and the other six genes of Asian H5N1-origin.The Clade 2.3.2.1c H5N1 reassortants displayed a high genetic relationship to a human H5N1 strain(A/Alberta/01/2014).Further analysis showed that similar viruses have been circulating in wild birds in China,Russia,Dubai(Western Asia),Bulgaria and Romania(Europe),as well as domestic poultry in some regions of Africa.The affected areas include the Central Asian,East Asian-Australasian,West Asian-East African,and Black Sea/Mediterranean flyways.These results show that the novel Clade 2.3.2.1c reassortant viruses are circulating worldwide and may have gained a selective advantage in migratory birds,thus posing a serious threat to wild birds and potentially humans. 关键词：H5N1 highly pathogenic avian influenza virus Clade 2.3.2.1c OUTBREAK migratory birds

相关文献

参考文献（27）
引证文献（7）
耦合文献（0）

参考文献(27)

引证文献(7)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Highly pathogenic avian influenza H5N1 Clade 2.3.2.1c virus in migratory birds,2014–2015

参考文献(27)

引证文献(7)

用户提示