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Polymorphism of POMC Gene in Guizhou Yellow Cattle

查看全文 作  者:Xu [1]Longxin;Liu [1]Jing;Zhang [1]Lin;He [1]Guangzhong 高影响力作者 机构地区:[1]Guizhou Institute of Animal Husbandry and Veterinary Medicine, Guiyang 550005, China高影响力机构 出  处:《Animal Husbandry and Feed Science》索引2016年第8卷第5期,共3页高影响力期刊 基  金:Science and Technology Fund of Guizhou Province[QKH J LNK(2013)No.6];Construction of Beef Cattle Industry Research System of Guizhou Province(GZCYTX-03) 摘  要:[Objective]The paper was to explore the effect of pro-opiomelanocortin (POMC) on feeding behavior and energy homeostasis of animals.[Method]Using DNA sequencing technology,polymorphisms of POMC gene in 92 individuals of Guizhou yellow cattle were studied.[Result]Five mutation sites,138 C> T,430 C> T,644 C> T,668 C> T,693 A> G,were found in the 870 bp amplification product.Polymorphism results showed that except the mutation site 430 C>T that was deviated from the Hardy-Weinberg equilibrium (HWE) state (P<0.05),the rest mutation sites were at the HWE state (P>0.05); the peptide information content (PIC) of five mutation sites were moderate polymorphism.[Conclusion]The POMC gene of Guizhou Yellow Cattle was abundant in genetic diversity,with great selection potential,which could be used as a potential genetic marker of cattle growth traits. 关 键 词:Guizhou yellow cattle POMC gene POLYMORPHISM
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