Nutrient patterns and risk of cataract:a case-control study

查看全文 作　　者：Fatemeh [1]Sedaghat;Matin [1]Ghanavati;Parisa Nezhad [1]Hajian;Sara [1]Hajishirazi;Mehdi [1]Ehteshami;Bahram [1]Rashidkhani

机构地区：[1]Department of Community Nutrition,Faculty of Nutrition Sciences and Food Technology,National Nutrition and Food Technology Research Institute (WHO Collaborating Center),Shahid Beheshti University of Medical Sciences

出　　处：《International Journal of Ophthalmology(English edition)》索引2017年第10卷第4期,共7页

基　　金：Supported by the National Nutrition and Food Technology Research Institute(NNFTRI)of Shahid Beheshti University of Medical Sciences,Tehran,Iran 摘　　要：AIM:To assess the relation between nutrient patterns and cataract risk.METHODS:This is a hospital-based case-control study with 97 cataract patients and 198 matched controls.Dietary consumption was collected through a valid food frequency questionnaire(FFQ).Nutrient patterns were detected by applying factor analysis.Unconditional logistic regression models were used to estimate odds ratio(ORs) and 95%CIs.RESULTS:We extracted 5 main nutrient patterns.Factor 1 included niacin,thiamin,carbohydrates,protein,zinc,vitamin B6 and sodium(sodium pattern).Factor 2 was characterized by oleic acid,monounsaturated fats,polyunsaturated fats,linoleic acid,trans fatty acid,linolenic acid,vitamin E and saturated fats(fatty acid pattern).The third factor represented high intake of vitamin B12,vitamin D,cholesterol and calcium(mixed pattern).The 4^(th) pattern was high in intake of beta and alpha carotene,vitamin A and vitamin C(antioxidant pattern).Finally,the 5^(th) pattern loaded heavily on docosahexaenoic acid(DHA) and eicosapentaenoic acid(EPA)(omega-3 pattern).In crude and multivariate analysis,the sodium pattern was associated with increased risk of cataract(OR=1.97,95%CI:1.09-3.96).The fatty acid pattern elevated the risk of cataract(OR=1.94,95%CI:1.1-3.86).Antioxidant pattern was associated with a significant 79% reduced risk(2^(nd) category compared with the 1st).Omega-3 pattern was significantly negatively associated with risk of cataract(P=0.04).CONCLUSION:These findings imply that nutrient patterns reflecting a combined consumption of nutrients might be important in the etiology of cataract.Additional studies with more efficient designs are warranted to confirm our findings. 关键词：滋养的模式奔流盒子控制学习

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Nutrient patterns and risk of cataract:a case-control study

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