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m^6A mRNA methylation sustains Treg suppressive functions

查看全文 作  者:Jiyu [1,2]Tong;Guangchao [2,3]Cao;Ting [1]Zhang;Esen [2]Sefik;Maria Carolina Amezcua [2]Vesely;James P [6]Broughton;Shu [4]Zhu;Huabin [5]Li;Bin [1]Li;Lei [1]Chen;Howard Y [6]Chang;Bing [1,2]Su;Richard A [2,7]Flavell;Hua-Bing [1,2]Li 高影响力作者 机构地区:[1]Shanghai Institute of Immunology, Department of Microbiology and Im-munology, Shanghai Jiao Tong University School of Medicine (SJTU-SM),Shanghai 200025, China;[2]Department of Immunobiology, Yale UniversitySchool of Medicine, New Haven, CT 06520, USA;[3]The First AffiliatedHospital Biomedical Translational Research Institute and GuangdongProvince Key Laboratory of Molecular Immunology and Antibody Engineering, Jinan University, Guangzhou, Guangdong 510632, China;[4]Institute of Immunology and the CAS Key Laboratory of Innate Immunity andChronic Disease, School of Life Sciences and Medical Center, Universityof Science and Technology of China, HefeL Anhui 230027, China;[5]Department of Otolaryngology, Head and Neck Surgery, Affiliated Eye, Ear,Nose and Throat Hospital, Fudan University, Shanghai 200031, China;[6]Center for Personal Dynamic Regulomes, Stanford University, Stanford,CA 94305, USA;[7]Howard Hughes Medical Institute, Chevy Chase, MD20815-6789, USA高影响力机构 出  处:《Cell Research》索引2018年第28卷第2期,共4页高影响力期刊 基  金:Acknowledgments We thank W Bailis, W Li, Kroehling L, J Alderman, C Lieber,J Stein and other members of the Flavell laboratory and the Li laboratory for discussions and technical support. This work was supported by Howard Hughes Medical Institute (RAF), the start- up fi.md from the Shanghai Jiao Tong University School of Medicine (H-BL), the Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning (H- BL), the National Natural Science Foundation of China (91753141 to H-BL, 81725004 to HL, 31470845 and 81430033 to BS, 81788104 and 31770990 to SZ), the US NIH R01-HG004361 and R35-CA209919 (HYC). 关 键 词:MRNA 支撑 镇压 化学药品 新陈代谢 蛋白质
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