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Diabetic kidney disease treated with a modified Shenzhuo formula derived from Traditional Chinese Medicine:a case report

查看全文 作　　者：Guo [1]Jing;Zhen [2]Hongdong;Zhao [3]Xiyan;Zhao [4]Linhua;Tong [4]Xiaolin 高影响力作者 机构地区：[1][1Department of Endocrinology,Guang'anmenHospital of China,Academy of Chinese Medical Sciences,Beijing 00054,China;[2]Department of Endocrinology,Guang'anmen Hospitat of China,Academy of Chinese Medical Sciences,Beijing 100054,China,Department of Endocrinology,Beijing Hepingli Hospital,Beiiina 100013.China;[3]Department of Endocrinology,Guang'anmen Hospital of China,Academy of Chinese Medical Sciences,Beijing 100054,China;[4]Department ot Molecular and Biology,Guang'anmen Hospital of China,Academy of Chinese Medical Sciences,Beijing 100054,China,Departmentof Endocrinology,Guang'anmen Hospital of China,Academy of Chinese Medical Sciences,Beijing 100054,China高影响力机构 出　　处：《Journal of Traditional Chinese Medicine》索引2017年第37卷第6期,共8页高影响力期刊 基　　金：Supported by the Major Program of the National Science Foundation of China(No.81430097);the Fundamental Research Funds for the Central Public Welfare Research Institutes(No.zz0808004) 摘　　要：INTRODUCTION: Diabetic kidney disease(DKD) is one of the most common microvascular complications of diabetes mellitus and is the leading cause of end-stage renal disease. DKD seriously affects the quality of life of patients and brings heavy economic burden to the country. At present, the pathogenesis of DKD is not entirely clear, and clinical treatment is mainly to control blood glucose and lower blood pressure and urine protein. However,the clinical effect is not satisfactory.CASE PRESENTATION: A female patient, aged 72 years, first visited our hospital endocrinology clinic,and was diagnosed with DKD. She suffered from fatigue, cold sensation in the lower extremities, convulsion of the lower limbs and frequent urination at night. She had a dark purple tongue with white and yellow fur and sublingual varices. Accessory examinations showed that her fasting blood glucose was 5.7 mmol/L, serum creatinine 159 μmol/L,blood urea nitrogen 13.6 μmol/L, blood uric acid493 μmol/L, and blood pressure 138/65 mm Hg.The patient received Traditional Chinese Medicine treatment of the modified Shenzhuo formula[Huangqi(Radix Astragali Mongolici), Dahuang(Radix Et Rhizoma Rhei Palmati), Shuizhi(Hirudo) and Danshen(Radix Salviae Miltiorrhizae)] for 7 years and achieved good results.CONCLUSION: This case provides a specific treatment plan and an effective reference for clinical application of Traditional Chinese Medicine for treating DKD. This may be an alternative treatment for DKD. 关 键 词：DIABETIC nephropathies Medicine, Chi-nese TRADITIONAL Shenzhuo FORMULA Case REPORTS
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