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Trend of blood lactate level in acute aluminum phosphide poisoning

查看全文 作　　者：Peyman [1]Erfantalab;Kambiz [2]Soltaninejad;Shahin [1]Shadnia;Nasim [1]Zamani;Hossein Hassanian-[1]Moghaddam;Arezou [1]Mahdavinejad;Behrooz Hashemi [1]Damaneh 高影响力作者 机构地区：[1]Toxicological Research Center,Excellent Center of Clinical Toxicology,Department of Clinical Toxicology,Loghman Hakim Hospital,School of Medicine,Shahid Beheshti University of Medical Sciences,Tehran,Iran;[2]Department of Forensic Toxicology,Legal Medicine Research Center,Legal Medicine Organization,Tehran,Iran高影响力机构 出　　处：《World Journal of Emergency Medicine》索引2017年第8卷第2期,共5页高影响力期刊 基　　金：supported by a grant from Toxicological Research Center of Shahid Beheshti University of Medical Sciences 摘　　要：BACKGROUND: Aluminum phosphide(Al P) poisoning is common in the developing countries. There is no specifi c antidote for the treatment of acute Al P poisoning. Early diagnosis of poisoning and outcome predictors may facilitate treatment decisions. The objective of this study was to determine the trend of blood lactate level in acute Al P poisoning to evaluate its role as a prognostic factor.METHODS: This was a prospective study on acute Al P intoxicated patients during one year. Demographic data, clinical and laboratory data on admission, and outcome were recorded in a selfmade questionnaire. Blood lactate levels were analyzed every two hours for 24 hours.RESULTS: Thirty-nine(27 male, 12 female) patients were included in the study. The mortality rate was 38.5%. The mean blood pressure, pulse rate, blood p H and serum bicarbonate level were significantly different between the survivors and non-survivors groups. Blood lactate level was signifi cantly higher in the non-survivors group during 8 to 16 hours post ingestion.CONCLUSION: Blood lactate level could be used as an index of severity of acute Al P poisoning. 关 键 词：Aluminum phosphide POISONING Blood lactate Prognostic factor
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