Assessment of the long-term visual and anatomical outcomes of ranibizumab to treat neovascular age-related macular degeneration

查看全文 作　　者：Bekir [1]Kücük;Sibel [1]Kadayifcilar;Bora [1]Eldem

机构地区：[1]Department of Ophthalmology,Hacettepe University,Ankara 06100,Turkey

出　　处：《International Journal of Ophthalmology(English edition)》索引2018年第11卷第4期,共5页

摘　　要：AIM: To investigate the long-term visual and anatomical outcomes of patients who underwent intravitreal ranibizumab monotherapy to treat neovascular age-related macular degeneration(AMD) and followed-up for at least 2 y.METHODS: A total of 74 eyes of 74 patients who underwent ranibizumab monotherapy for neovascular AMD were included in this retrospective study.RESULTS: The average patient age was 72.1±6.5(range, 57-85)y, the average follow-up time 46.2±13.1(range, 24-75)mo, and the average number of visits 24.1±9.5(range, 8-48). The mean number of injections in year 1 was 4.5, 1.6 in year 2, 0.9 in year 3, 0.4 on year 4, and 0.1 in the following years. Within the entire follow-up period, the mean number of injections was 7.6±4.4(range, 2-21). The mean visual acuity was 48.1±15(range, 15-76) letters at baseline and 45.7±19(range, 7-75) at year 5. The mean central macular thickness was 303±78(range, 178-552) μm at baseline and 251±51(range, 138-359) μm at year 5. Scars developed in 47(63.5%) eyes at the end of the follow-up period, and atrophy was evident in 6(8.1%) eyes.CONCLUSION: Ranibizumab monotherapy can stabilize visual acuity for a mean period of 4 y in patients with neovascular AMD. 关键词：intravitreal 注射 neovascular 年龄相关的有斑点的退化 RANIBIZUMAB

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Assessment of the long-term visual and anatomical outcomes of ranibizumab to treat neovascular age-related macular degeneration

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