42,573 cases of hepatectomy in China: a multicenter retrospective investigation

查看全文 作　　者：Binhao [1]Zhang;Bixiang [1]Zhang;Zhiwei [1]Zhang;Zhiyong [1]Huang;Yifa [1]Chen;Minshan [4]Chen;Ping [5]Bie;Baogang [6]Peng;Liqun [7]Wu;Zhiming [8]Wang;Bo [9]Li;Jia [10]Fan;Lunxiu [11]Qin;Ping [12]Chen;Jingfeng [13]Liu;Zhe [14]Tang;Jun [15]Niu;Xinmin [16]Yin;Deyu [17]Li;Songqing [18]He;Bin [19]Jiang;Yilei [3]Mao;Weiping [2]Zhou;Xiaoping [1]Chen

机构地区：[1]Institute of Hepato-pancreato-bililary Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;[2]Eastern Hepatobiliary Surgery Hospital, Shanghai 201805, China;[3]Union Hospital, Beijing 100032, China;[4]Cancer Hospital of Sun Yat-sen University, Guangzhou 510060, China;[5]Southwest Hospital, Chongqing 400038, China;[6]The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China;[7]Affiliated Hospital of Qingdao Medical College, Qingdao 266071, China;[8]Xiangya Hospital, Changsha 410008, China;[9]West China Hospital, Chengdu 610041, China;[10]Zhongshan Hospital of Fudan University, Shanghai 200032, China;[11]Huashan Hospital of Fudan University, Shanghai 100044. China;[12]Daping Hospttal, the Third Military Medical University, Chongqing 400042, China;[13]Mengchao Hepatobiliary Hospital, Fuzhou 350025, China;[14]The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China;[15]Qilu Hospital of Shandong University, Jinan 250012, China;[16]Hunan People's Hospital, Changsha 410002, China;[17]Henan People's Hospital, Zhengzhou 450003, China;[18]The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China;[19]Taihe Hospital, Shiyan 442000, China

出　　处：《Science China(Life Sciences)》索引2018年第61卷第6期,共11页

基　　金：supported by the State Key Project on Inflectional Disease of China(2012ZX10002016-004,2012ZX 10002010-001-004);the Chinese Ministry of Public Health for Key Clinical Projects(439,2010)to Prof.Xiaoping Chen;the National Natural Science Foundation of China(81502524)to Dr.Binhao Zhang 摘　　要：Hepatectomy is currently routinely performed in most hospitals in China. China owns the largest population of liver diseases and the biggest number of liver resection cases. A nationwide multicenter retrospective investigation involving 112 hospitals was performed, and focused on liver resection for patients with hepatocellular carcinoma(HCC). 42,573 cases of hepatectomy were enrolled, and 18,275 valid cases of liver resection for HCC patients were selected for statistical analysis. The epidemiology of HCC, distribution of hepatectomy, postoperative complications and prognosis were finally analyzed. In the 18,275 HCC patients,81% had hepatitis B virus infection and 10% had hepatitis C virus infection. 38% of the HCC patients had normal Alphafetoprotein(AFP) level, and other 35% had an AFP level lower than 400 ng mL^(-1). In the study period, 97% of the hepatectomy for HCC were treated with open surgery, and 23.81% had vascular exclusion techniques. The operation time was(191.7±105.6) min,the blood loss was(546.0±562.8) m L, and blood transfusion was(543.0±1,035.2) m L. The median survival for HCC patients was 631 days, with 1-, 3-, and 5-year overall survival of 73.2%, 28.8% and 19.6%, respectively. Liver cirrhosis, multiple nodules,tumor thrombosis and high AFP level were risk factors that affect postoperative survival. 关键词：盒子中国病毒感染肝疾病 HCC 切除术统计分析传染病学

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42,573 cases of hepatectomy in China: a multicenter retrospective investigation

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