Discovery and biosynthesis of thioviridamide-like compounds

查看全文 作　　者：Jian [1]Tang;Jingxia [1]Lu;Qunfeng [1]Luo;Huan [1]Wang

机构地区：[1]State Key Laboratory of Coordination Chemistry,Jiangsu Key Laboratory of Advanced Organic Materials,School of Chemistry and Chemical Engineering,Nanjing University

出　　处：《Chinese Chemical Letters》索引2018年第29卷第7期,共7页

基　　金：supported by the 1000-Youth Talents Plan, NSF of China (No. 21778030);Natural Science Foundation of Jiangsu Province (No. BK20160640);the Fundamental Research Funds for the Central Universities 摘　　要：Thioviridamide-like compounds are a unique subfamily of ribosomally synthesized and post-translationally modified peptides and contain characteristic thioamide bonds and S-[(Z)-2-aminovinyI]-Dcysteine(AviCys). Members of this family are active against a number of cancer cell lines. The distribution, biosynthetic machinery and the mode of action of thioviridamide-like compounds remain largely unknown. In this review, we outlined recent advances in the discovery of thioviridamide-like peptide natural products and the effort in the elucidation of their biosynthetic origin. 关键词：NATURAL products THIOAMIDES RiPPs BIOSYNTHESIS

相关文献

参考文献（25）
引证文献（1）
耦合文献（0）

参考文献(25)

引证文献(1)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Discovery and biosynthesis of thioviridamide-like compounds

参考文献(25)

引证文献(1)

用户提示