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Ocular hypertension in patients with central/hemicentral retinal vein occlusions: cumulative prevalence and management

查看全文 作　　者：Dan [1]Calugaru;Mihai [1]Calugaru;Stefan [2]Talu 高影响力作者 机构地区：[1]Department of Ophthalmology, University of Medicine, Cluj-Napoca 400467, Romania;[2]Department of AET Discipline of Descriptive Geometry and Engineering Graphics, Faculty of Mechanical Engineering,Technical University of Cluj-Napoca, Cluj-Napoca 400012,Romania高影响力机构 出　　处：《International Journal of Ophthalmology(English edition)》索引2018年第11卷第7期,共6页高影响力期刊 摘　　要：● AIM: To prospectively evaluate the cumulative prevalence and the management of ocular hypertension(OH) in patients with unilateral acute central/hemicentral retinal vein occlusions(C/HCRVOs) over the course of 3 y.● METHODS: The study included 57 patients with unilateral acute C/HCRVOs. All patients underwent a comprehensive ophthalmological examination of both eyes. OH associated with C/HCRVO in patients showing a score >5% for the risk of conversion to primary open angle glaucoma(POAG) was treated with OH medication. The treatment aimed for a decrease in intraocular pressure(IOP) to <21 mm Hg with a >22% reduction from the initial values. The cumulative prevalence of OH and the effectiveness of treatment assessed by the cumulative prevalence of conversion from OH to POAG, were estimated.● RESULTS: Fifteen patients had OH associated with C/HCRVOs, the cumulative prevalence of OH was 29.4%(95% confidence interval, 16.9-41.9). The mean value of the risk score of OH conversion to POAG for the 5 subsequent years was 11.7%±5.4%. The IOP significantly decreased from 25.67±2.16 mm Hg to 18.73±2.96 mm Hg. None of the OH patients converted to POAG during the follow-up period. ● CONCLUSION: The increased cumulative prevalence of OH in C/HCRVO patients indicates that OH is a risk factor for the appearance of venous occlusion. Patients with OH associated with C/HCRVO must be considered to be at high risk for conversion to POAG. Treatment with OH medications prevented conversion to POAG during the 3-year follow-up. 关 键 词：ocular hypertension acute central/hemicentral retinal vein occlusion::intraocular pressure::primary openangle glaucoma risk factor.
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