Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis

查看全文 作　　者：Yao [1]Chen;Yuxuan [2,3,4]Zheng;Yun [2,3,4]Gao;Zhen [1]Lin;Suming [1]Yang;Tongtong [1]Wang;Qiu [1]Wang;Nannan [1]Xie;Rong [2]Hua;Mingxi [5]Liu;Jiahao [5]Sha;Michael D. [6]Griswold;Jinsong [1]Li;Fuchou [2,3,4]Tang;Ming-Han [1]Tong

机构地区：[1]State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cetl Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China;[2]Beijing Advanced Innovation Center for Genomics, Biomedical institute for Pioneering Investigation via Convergence, College of Life Sciences, Peking University, Beijing 100871, China;[3]Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing 100871, China;[4]Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China;[5]State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu 211166, China;[6]School of Molecular Biosciences and the Center for Reproductive Biology, Washington State University, Pullman, WA, USA

出　　处：《Cell Research》索引2018年第28卷第9期,共18页

基　　金：We thank Dr. M. Handel (The Jackson Laboratory) for anti-Hlt antisera; Drs. Zhenge Luo (Shanghai institute of Neuroscience), and Fei Lan (Fudan University) for experimental support; and Dr Jinqiu Zhou (Shanghai institute of Biochemistry and Cell Biology) for helpful discussion and critical reading of the manuscript. M.-H,T. was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB19000000), the Ministry of Science and Technology of China (2014CB943101), the National Key Research and Development Program of China (2016YFC1000600), SIBS foundation, the National Natural Science Foundation of China (31471401 and 31671553). F.T. was supported by the National Natural Science Foundation of China (31625018). J.S. was supported by the National Key Research and Development Program of China (2017YFA0103803), the Shanghai Municipal Commission for Science and Technology Grants (17411954900). M.L was supported by the National Natural Science Foundation of China (31571536). We thank the Genome Tagging Project Center for technical support. We thank the Histology, Flow Cytometry, and Vivarium services at SIBCB. 关键词：精子发生管理者房间老鼠发展潜力哺乳动物转基因开发

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Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis

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