Influence of Vitamin E on Preventive or Therapeutic Effect of MFA and DTPA in Cadmium Toxicity

查看全文 作　　者：[1]S.K.TANDON;[2]S.SINGH 机构地区：[1]IndustrialToxicologyResearchCentre,PostBoxNo.80,MahatmaGnadhiMarg,Lucknow226001,India;[2]IndustrialToxic 出　　处：《Biomedical and Environmental Sciences》索引1995年第8卷第1期,共6页 摘　　要：The influence of vitamin E supplementation on the ability of α-mercapto-β(2-furyl)acrylic acid (MFA) or calcium trisodium dicthylenetriamine pentaacetate (DTPA) to reduce body burden of cadmium and reverse Cd-induced biochemical alterations was investigated in Cd-exposed rats. The treatment with MFA-vitamin E or CaNa3 DTPAvitandn E was more effective than either vitamin E or chelating agent alone, in depleting blood and tissue Cd. However, the combined treatment showed only limited advantage over the individuals in restoring Cd-induced biochemical changes. Further, the treatment with chelator-vitamin E concomitantly with the exposure to Cd was more effective than post-Cd exposure treatment. 关 键 词：维生素E VE MFA DTPA 镉毒性 预防作用 治疗效果 影响