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Observation or resection of pancreatic intraductal papillary mucinous neoplasm:An ongoing tug of war

查看全文 作　　者：Jan Rune [1]Aunan;Nigel [2,3]B.Jamieson;Kjetil [1,4,5]Sφreide 高影响力作者 机构地区：[1]Department of Gastrointestinal Surgery,HPB Unit,Stavanger University Hospital,Stavanger 4068,Norway;[2]Wolfson Wohl Cancer Research Centre,Institute of Cancer Sciences,University of Glasgow,Glasgow G611BD,United Kingdom;[3]West of Scotland Pancreatic Unit,Glasgow Royal Infirmary,Glasgow G40SF,United Kingdom;[4]Gastrointestinal Translational Research Unit,Laboratory for Molecular Medicine,Stavanger University Hospital,Stavanger 4068,Norway;[5]Department of Clinical Medicine,University of Bergen,Bergen 5003,Norway高影响力机构 出　　处：《World Journal of Gastrointestinal Oncology》索引2019年第11卷第12期,共9页高影响力期刊 摘　　要：An increasing number of patients are being referred to pancreatic centres around the world due to often incidentally discovered cystic neoplasms of the pancreas.The evaluation and management of pancreatic cystic neoplasms is a controversial topic and with existing guidelines based on a lack of strong evidence there is discordance between centres and guidelines with regard to when to offer surgery and when to favour surveillance.The frequency,duration and modality of surveillance is also controversial as this is resource-consuming and must be balanced against the perceived benefits and risks involved.While there is consensus that the risk of malignancy should be balanced against the lifeexpectancy and comorbidities,the indications for surgery and surveillance strategies vary among the guidelines.Thus,the tug of war between surveillance or resection continues.Here we discuss the recommendations from guidelines with further accumulating data and emerging reports on intraductal papillary mucinous neoplasm in the literature. 关 键 词：NEOPLASIA Pancreatic cancer Pancreatic cyst Diagnosis RESECTION Surveillance Mutation Biomarker
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