Diabetic retinopathy: a matter of retinal ganglion cell homeostasis

查看全文 作　　者：Elisabetta [1]Catalani;Davide [1]Cervia

机构地区：[1]Department for Innovation in Biological, Agro-food and Forest systems (DIBAF), Università degli Studi della Tuscia,largo dell’Università snc

出　　处：《Neural Regeneration Research》索引2020年第15卷第7期,共2页

基　　金：supported by grants from the Italian Ministry of Education,University and Research:“PRIN2015” to DC and “Departments of Excellence-2018”Program(Dipartimenti di Eccellenza)(Department for Innovation in Biological,Agro-food and Forest systems-DIBAF-University of Tuscia,Viterbo,Italy)(Project “Landscape 4.0-food,wellbeing and environment”) 摘　　要：Diabetic retinopathy(DR)is the most common complication of diabetes and the leading cause of visual impairment in the working-age population in the Western world(http://gffzzc722d8cd65ac40e7h5bkb6xn990006vuk.ffgz.tsg.suse.edu.cn/).One of the earliest events observed in DR is the impairment of retinal perfusion,caused by the constriction of retinal blood vessels,inducing biochemical and metabolic alterations,perycites/endothelial degeneration,and retina ischemia(Wong et al.,2016).Severe stages of DR include proliferative DR,caused by the abnormal growth of new vessels,and diabetic macular oedema in the central part of the retina.DR is strongly associated with a prolonged duration of diabetes,hypertension,and hyperglycaemia but it can persist even after replacement of normal glycaemic status(Wong et al.,2016). 关键词：HOMEOSTASIS alterations IMPAIRMENT

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Diabetic retinopathy: a matter of retinal ganglion cell homeostasis

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