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Red blood cell distribution width: A marker of anisocytosis potentially associated with atrial fibrillation

查看全文 作  者:Giuseppe [1]Lippi;Gianfranco [2]Cervellin;Fabian Sanchis-[3]Gomar 高影响力作者 机构地区:[1]Section of Clinical Biochemistry,University of Verona,Verona 37134,Italy;[2]Emergency Department,University Hospital of Parma,Parma 43126,Italy;[3]Department of Physiology,Faculty of Medicine,University of Valencia and INCLIVA Biomedical Research Institute,Valencia 46010,Spain高影响力机构 出  处:《World Journal of Cardiology》索引2019年第11卷第12期,共13页高影响力期刊 摘  要:The incorporation of biomarkers in the actually used risk scores seem to be helpful for early identifying atrial fibrillation(AF)patients at higher risk.The aim of this critical review of the scientific literature is to investigate the potential clinical significance of red blood cell distribution width(RDW)in AF.A systematic electronic search was carried out to identify all articles describing an epidemiological association between RDW and AF in adult human populations.Data abstraction was conducted on a final number of 35 articles(13 crosssectional,12 prospective and 10 retrospective studies).The results of these epidemiological investigations were all virtually concordant to emphasize that an enhanced RDW value is not only a predictive factor and a marker of AF but its measurement may also be helpful for predicting the risk of developing many adverse complications in patients with AF,such as recurrence and duration of AF,hospitalization for heart failure,bleeding,left atrial thrombosis and stasis,thromboembolic events and mortality.AF patients with RDW values exceeding the local reference range may be more aggressively investigated and managed,in order to identify and attenuate the impact of possible underlying disorders causing both anisocytosis and AF. 关 键 词:Atrial fibrillation ARRHYTHMIA Erythrocytes Red blood cell distribution width
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