Surface molecular imprinting on g-C3N4 photooxidative nanozyme for improved colorimetric biosensing

查看全文 作　　者：Yuanheng [1]Wu;Qiang [2]Chen;Shuang [1]Liu;Hua [1]Xiao;Menglin [1]Zhang;Xinfeng [1,2]Zhang

机构地区：[1]College of Materials and Chemistry&Chemical Engineering,Chengdu University of Technology,Chengdu 610059,China;[2]College of Environment and Ecology,Chengdu University of Technology,Chengdu 610059,China

出　　处：《Chinese Chemical Letters》索引2019年第30卷第12期,共5页

基　　金：the financial support from the National Natural Science Foundation of China(No.21475013);the Sichuan Science and Technology Project(No.2018JY0466) 摘　　要：Graphitic carbon nitride(g-C3 N4),as a visible-light-active organic semiconductor,has attracted growing attentions in photocatalysis and photoluminescence-based biosensing.Here,we demonstrated the intrinsic photooxidase activity of g-C3 N4 and then surface molecular imprinting on g-C3 N4 nanozymes was achieved for improved biosensing.Upon blue LED irradiation,the g-C3 N4 exhibited superior enzymatic activity for oxidation of chromogenic substrate like 3,3’,5,5’-tetramethylbenzidine(TMB)without destructive H2 O2.The oxidation was mainly ascribed to ·O2^-that was generated during light irradiation.The surface molecular imprinting on g-C3 N4 can lead to an over 1000-fold alleviation in matrix-interference from serum samples,4-fold improved enzymatic activity as well as enhanced substrate specificity comparing with bare g-C3 N4 during colorimetric sensing.Also,the MIP-g-C3 N4 possesses a high affinity to TMB with a Km value of only 22 μmol/L,much lower than other comment nanozymes like AuNPs,Fe3 O4 NPs,etc.It was successfully applied for detection of cysteine in serum sample with satisfactory recoveries. 关键词：Molecularly imprinted polymer Graphitic carbon nitride Nanoenzyme COLORIMETRY BIOSENSING

相关文献

参考文献（35）
引证文献（2）
耦合文献（0）

参考文献(35)

引证文献(2)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Surface molecular imprinting on g-C3N4 photooxidative nanozyme for improved colorimetric biosensing

参考文献(35)

引证文献(2)

用户提示