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Pathophysiology and Individualized Management of Vasovagal Syncope and Postural Tachycardia Syndrome in Children and Adolescents:An Update

查看全文 作  者:Ying [1]Liao;Junbao [1]Du 高影响力作者 机构地区:[1]Department of Pediatrics,Peking University First Hospital,Beijing 100034,China高影响力机构 出  处:《Neuroscience Bulletin》索引2020年第36卷第6期,共15页高影响力期刊 基  金:supported by Peking University Clinical Scientist Program (BMU2019LCKXJ001,Beijing);Fundamental Research Funds for the Central Universities of China. 摘  要:Vasovagal syncope(VVS) and postural tachycardia syndrome(POTS) are the main forms of orthostatic intolerance in pediatrics and both are underlying causes of neurally-mediated syncope.In recent years,increasing attention has been paid to the management of VVS and POTS in children and adolescents.A number of potential mechanisms are involved in their pathophysiology,but the leading cause of symptoms varies among patients.A few studies thus have focused on the individualized treatment of VVS or POTS based on selected hemodynamic parameters or biomarkers that can predict the therapeutic effect of certain therapies and improve their effectiveness.This review summarizes the latest developments in individualized treatment of VVS and POTS in children and indicates directions for further research in this field. 关 键 词:Vasovagal syncope Postural tachycardia syndrome Individualized management PATHOPHYSIOLOGY CHILDREN Adolescents
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