GOECP/SEOR radiotherapy guidelines for small-cell lung cancer

查看全文 作　　者：Felipe [1]Couñago;Carolina de la [2]Pinta;Susana [3]Gonzalo;Castalia [4]Fernández;Piedad [5]Almendros;Patricia [6]Calvo;Begoña [6]Taboada;Antonio Gómez-[6]Caamaño;JoséLuis López [7]Guerra;Marisa [8]Chust;JoséAntonio [9]GonzálezFerreira;AnaÁlvarez [10]González;Francesc [11]Casas

机构地区：[1]Department of Radiation Oncology,Hospital Universitario Quirónsalud Madrid,Hospital La Luz,Universidad Europea de Madrid,Madrid 28223,Madrid,Spain;[2]Department of Radiation Oncology,Hospital Universitario Ramón y Cajal,Madrid 28034,Spain;[3]Department of Radiation Oncology,Hospital Universitario La Princesa,Madrid 28006,Spain;[4]Department of Radiation Oncology,GenesisCare Madrid,Madrid 28043,Spain;[5]Department of Radiation Oncology,Hospital General Universitario,Valencia 46014,Spain;[6]Department of Radiation Oncology,Hospital Clínico Universitario Santiago de Compostela,Santiago de Compostela 15706,Spain;[7]Department of Radiation Oncology,Hospital Universitario Virgen del Rocío,Sevilla 41013,Spain;[8]Department of Radiation Oncology,Fundación Instituto Valenciano de Oncología,Valencia 46009,Spain;[9]Department of Radiation Oncology,GenesisCare-Spain,Sevilla 41092,Spain;[10]Department of Radiation Oncology,HGU Gregorio Marañón,Madrid 28007,Spain;[11]Department of Radiation Oncology,Thoracic Unit,Hospital Clinic,Barcelona 08036,Spain

出　　处：《World Journal of Clinical Oncology》索引2021年第12卷第3期,共29页

摘　　要：Small cell lung cancer(SCLC)accounts for approximately 20%of all lung cancers.The main treatment is chemotherapy(Ch).However,the addition of radiotherapy significantly improves overall survival(OS)in patients with non-metastatic SCLC and in those with metastatic SCLC who respond to Ch.Prophylactic cranial irradiation reduces the risk of brain metastases and improves OS in both metastatic and non-metastatic patients.The 5-year OS rate in patients with limited-stage disease(non-metastatic)is slightly higher than 30%,but less than 5%in patients with extensive-stage disease(metastatic).The present clinical guidelines were developed by Spanish radiation oncologists on behalf of the Oncologic Group for the Study of Lung Cancer/Spanish Society of Radiation Oncology to provide a current review of the diagnosis,planning,and treatment of SCLC.These guidelines emphasise treatment fields,radiation techniques,fractionation,concomitant treatment,and the optimal timing of Ch and radiotherapy.Finally,we discuss the main indications for reirradiation in local recurrence. 关键词：Small cell lung cancer Chemotherapy Hyperfractionated radiation therapy Prophylactic brain irradiation Brain metastases REIRRADIATION

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GOECP/SEOR radiotherapy guidelines for small-cell lung cancer

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