Clinical evaluations of mineralized collagen in the extraction sites preservation

查看全文 作　　者：Lu [1,2]Feng;Liang [3]Zhang;Yun [4]Cui;Tian-Xi [4]Song;Zhi-Ye [4,5]Qiu;Xiu-Mei [5]Wang;Bao-Sheng [2]Tan

机构地区：[1]Department of Stomatology,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;[2]Beijing Stomatological Hospital,Capital Medical University,Beijing 100050,China;[3]Second Outpatient Department,General Hospital of Beijing Military Region,Beijing 100125,China;[4]Beijing Allgens Medical Science and Technology Co.,Ltd.,Beijing 100176,China;[5]State Key Laboratory of New Ceramics and Fine Processing,School of Materials Science and Engineering,Tsinghua University,Beijing 100084,China

出　　处：《Regenerative Biomaterials》索引2016年第3卷第1期,共8页

基　　金：supported by the National Basic Research Program of China(973 Program,2011CB606205);the‘Twelfth Five-Year’National Science and Technology Support Program(2012BAI17B02);the Ministry of Science and Technology of China and the National Natural Science Foundation of China(Grant Nos.21371106 and 51402167). 摘　　要：The purpose of this study was to explore the different effects between biomimetic mineralized collagen(MC)and ordinary physically blended hydroxyapatite/collagen(HA/Col)composite in evaluating new bone formation and regenerated bone height in human extraction sockets.Thirty-four patients who cannot retain teeth caused by trauma or decay were randomly selected from Department of Stomatology of Dongzhimen Hospital from December 2013 to December 2014.The patients were randomly divided into two groups.After the operation of tooth extraction,17 patients were implanted with biomimetic MC(MC group),and other 17 patients were implanted with ordinary physically blended nHA/Col composite(nHA/Col group).X-ray positioning projection by auto-photographing was taken to test the distance between the lowest position and the neighboring CEJm-CEJd immediately,1 month and 3 months after the operation.The height of new bone formation of the MC group was significantly higher than the nHA/Col group.Biomimetic MC showed better clinical outcomes in the bone formation for extraction site preservation and would have broad application prospect in the field of oral and maxillofacial surgeries. 关键词：mineralized collagen BIOMIMETIC extraction site preservation bone formation height

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Clinical evaluations of mineralized collagen in the extraction sites preservation

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