Research Progress of the Antiviral Bioactivities of Natural Flavonoids

查看全文 作　　者：Lin [1]Wang;Junke [1]Song;Ailin [1]Liu;Bin [2]Xiao;Sha [1]Li;Zhang [1]Wen;Yang [1]Lu;Guanhua [1]Du

机构地区：[1]Beijing Key Laboratory of Drug Targets Identification and Drug Screening,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,1 Xian Nong Tan Street,Beijing 100050,China;[2]Laboratory of Clinical Pharmacy,Ordos Central Hospital,Ordos School of Clinical Medicine,Inner Mongolia Medical University,Ordos 017000,China

出　　处：《Natural Products and Bioprospecting》索引2020年第10卷第5期,共13页

基　　金：supported by CAMS Innovation Fund for Medical Sciences(Grant No.2017-I2M-1-010);National Key Research and Development Program(Grant No.2018YFC0311005);National Science and Technology Major Projects(Grant No.2018ZX09711001-012). 摘　　要：Flavonoids are now considered as an indispensable component in a variety of nutraceutical and pharmaceutical applications.Most recent researches have focused on the health aspects of flavonoids for humans.Especially,different flavonoids have been investigated for their potential antiviral activities,and several natural flavonoids exhibited significant antiviral properties both in vitro and in vivo.This review provides a survey of the literature regarding the evidence for antiviral bioactivities of natural flavonoids,highlights the cellular and molecular mechanisms of natural flavonoids on viruses,and presents the details of most reported flavonoids.Meanwhile,future perspectives on therapeutic applications of flavonoids against viral infections were discussed. 关键词：Antiviral bioactivities Natural flavonoids Cellular and molecular mechanisms Therapeutic applications

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Research Progress of the Antiviral Bioactivities of Natural Flavonoids

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