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The network of cytokines,receptors and transcription factors governing the development of dendritic cell subsets

查看全文 作  者:Priyanka [1,2]Sathe;Li [1,3]Wu 高影响力作者 机构地区:[1]Walter and Eliza Hall Institute,1G Royal Parade,Parkville,Victoria 3050,Australia;[2]Department of Medical Biology,University of Melbourne,Australia;[3]Tsinghua University School of Medicine,Beijing 100084,China高影响力机构 出  处:《Protein & Cell》索引2011年第2卷第8期,共11页高影响力期刊 摘  要:The pathways leading to the development of different dendritic cell(DC)subsets have long been unclear.In recent years,a number of precursors on the route to DC development,both under steady state and inflammatory conditions,have been described,and the nature of these pathways is becoming clearer.In addition,the development of various knockout mouse models and an in vitro system modelling DC development have revealed the role of numerous cytokines and transcription factors that influence DC development.Here,we review recent findings on the factors important in DC development in the context of the developmental pathways that have been described. 关 键 词:dendritic cell CYTOKINES RECEPTORS transcription factors
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