The potential mechanism and prognosis value of Fructus tribuli treating breast cancer by netw ork-based pharmacological analysis

查看全文 作　　者：Lin [1]Dongjing;Li [1]Songyan;Zhang [1]Jun;[1]XuLu;Liu [1]Yang;Wang [1]Hongjun;Liu [1]Zhongping;Tian [1]Hongyan;Xu [1]Ye 机构地区：[1]Key Laboratory of Targeted Tumor Therapy and Translat ional Medicine,Department of Histology and Embryology,Department of Cell Biology,Department of Medical Genetics,Jilin University of Medicine,Jilin 132013 出　　处：《解剖学杂志》索引2021年第44卷第S01期,共2页 摘　　要：To screen effective active com pounds and targets of Fructus Tribuli(FT)for breast cancer,to further explore its molecular mechanism and compare the prognostic reliability of breast cancer patients.The potential active components of FT was screened using the TCMSP database.Relevant targets of breast cancer were collected on the GeneCards and OMIM databases.The biological processes,and pathways of FT anti-breast cancer were predicted by constructing the relationship network of herb-component-target using GO,KEGG,STRING.Survival of these the most significant differentially expressed genes were evaluated using KM database.7 main active components and 13 main targets for the treatment of breast cancer were identified. 关 键 词：BREAST cancer SURVIVAL