A high strength, wear and corrosion-resistant, antibacterial and biocompatible Nb-5 at.% Ag alloy for dental and orthopedic implants

查看全文 作　　者：Tian [1]Wan;Kangjie [1]Chu;Ju [1]Fang;Chuanxin [1]Zhong;Yiwen [1]Zhang;Xiang [2]Ge;Yonghui [3]Ding;Fuzeng [1]Ren 机构地区：[1]Department of Materials Science and Engineering,Southern University of Science and Technology,Shenzhen,China;[2]Key Laboratory of Mechanism Theory and Equipment Design of Ministry of Education,School of Mechanical Engineering,Tianjin University,Tianjin,300354,China;[3]Center for Advanced Regenerative Engineering,Department of Biomedical Engineering,Northwestern University,Evanston,IL,60208,USA 出　　处：《Journal of Materials Science & Technology》索引2021年第21期,共13页 基　　金：financially supported by the Natural Science Foundation of Guangdong(Grant No.2019A1515011755);the Fundamental Research Program of Shenzhen(Grant Nos.JCYJ20170412153039309 and JCYJ20170307110418960);the Natural Science Foundation of Tianjin(General Program,No.18JCYBJC19500),China。 摘　　要：Refractory metal niobium(Nb) incorporated with a small amount of silver(Ag),the resulting Nb-Ag twophase alloys,were fabricated by mechanical alloying and spark plasma sintering.The microstructure,mechanical properties,wear resistance,corrosion behavior,in vitro and in vivo antibacterial properties and biocompatibility of the Nb-Ag alloys were systematically investigated.The results show that the mechanical properties,wear resistance,corrosion resistance and antibacterial ability were significantly enhanced after addition of 5 at.% Ag.The fabricated Nb-5 at.% Ag alloy demonstrates high yield strength of up to ~1486 MPa and fracture strain of ~35 %.The precipitated Ag particles could reduce friction and wear.The enhanced corrosion resistance was attributed to the higher relative density of the sintered alloys and the formation of a stable and dense passive film of niobium and silver oxides.In vitro and in vivo evaluations show that the Nb-5 at.% Ag alloy also has strong antibacterial activity and good biocompatibility and osteointegration ability.These results demonstrate great potential of the nanostructured Nb-Ag alloys for dental and orthopedic implants. 关 键 词：Nb-Ag alloys WEAR CORROSION ANTIBACTERIAL BIOCOMPATIBILITY