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Young-onset colorectal cancer:A review

查看全文 作  者:Joy Zhou [1]Done;Sandy H [2]Fang 高影响力作者 机构地区:[1]Department of Surgery,Johns Hopkins Hospital,Baltimore,MD 21287,United States;[2]Department of Surgery,Johns Hopkins University School of Medicine,Johns Hopkins Hospital,Baltimore,MD 21287,United States高影响力机构 出  处:《World Journal of Gastrointestinal Oncology》索引2021年第13卷第8期,共11页高影响力期刊 摘  要:Despite the general decrease in overall incidence of colorectal cancer since the early 1990s,the incidence of colorectal cancer in patients less than 50 years old has nearly doubled.A systematic review was performed using the PubMed database(2011-2020)and Cochrane Database of Systematic Reviews(2011-2021)to identify studies(published in English)evaluating epidemiologic,clinical,hereditary,and molecular features;as well as evaluation,management,and prognosis of youngonset colorectal cancer patients.Our search yielded a total of 3401 articles,after applying our inclusion criteria.We fully reviewed 94 full-length studies.This systematic review demonstrates the increasing incidence of young-onset colorectal cancer and highlights the importance of being hypervigilant for the differential diagnosis colorectal cancer when evaluating a young adult who presents with gastrointestinal symptoms. 关 键 词:Young-onset colorectal cancer Early-onset colorectal cancer Colorectal cancer Genetic Young adult HEREDITARY
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