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Colletodiphenol A,a new phenol derivative isolated from the endophytic fungus Colletotrichum capsici

查看全文 作  者:Guiyang [1]Xia;Yanbin [2]Sun;Yuzhuo [1]Wu;Huan [1]Xia;Pengcheng [3]Lin;Sheng [1,2]Lin 高影响力作者 机构地区:[1]Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;[2]State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China;[3]College of Pharmaceutical Sciences,Qinghai university for nationalities,Xining 810000,People’s Republic of China高影响力机构 出  处:《Asian Journal of Traditional Medicines》索引2021年第16卷第4期,共6页高影响力期刊 基  金:This work was financially supported by the National Natural Science Foundation of China(NNSFC,Grant No.81803397 and 81773589);the Fundamental Research Funds for the Central Universities(Grant No.3332018088);the Science and Technology program of Qinghai(Grant No.2018-ZJ-739);the Innovation Platform for the Development and Construction of Special Project of Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province(Grant No.2020-ZJ-Y20). 摘  要:A new C_(6)-C_(2)dimer phenol derivative,colletodiphenol A(1),along with two known C_(6)-C_(2)phenol derivatives(2,3)were isolated from the endophytic fungus Colletotrichum capsici related to the traditional Chinese medicine Paeonia lactiflora.Their structures were elucidated based on extensive spectroscopic data analysis,including HRESIMS,UV,IR,1D and 2D NMR.The antioxidant and anti-inflammatory activities of the isolated compounds were evaluated,but none of them displayed significant activity. 关 键 词:Endophytic fungi Colletotrichum capsici Paeonia lactiflora Pall. PHENOLS secondary metabolites
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