Follow-up outcomes in patients with negative initial colon capsule endoscopy findings

查看全文 作　　者：Konosuke [1]Nakaji;Mitsutaka [1]Kumamoto;Mikiko [1]Yodozawa;Kazuki [1]Okahara;Shigeo [2]Suzumura;Yukinori [1]Nakae

机构地区：[1]Endoscopy Center,Aishinkai Nakae Hospital,Wakayama-shi 640-8461,Wakayama,Japan;[2]Internal Medicine,Japanese Red Cross Urakawa Hospital,Higashichochinomi,Urakawagun Urakawacho 057-0007,Hokkaido,Japan

出　　处：《World Journal of Gastrointestinal Endoscopy》索引2021年第13卷第10期,共8页

摘　　要：BACKGROUND Colon capsule endoscopy(CCE),which became clinically applicable in 2006,is a simple and noninvasive procedure to evaluate colonic diseases;the accuracy of second-generation CCE,introduced in 2009,has dramatically improved.Currently,CCE is used as an alternative method for colorectal cancer screening,as well as for evaluating the mucosal lesions of inflammatory bowel disease,in cases where performing colonoscopy(CS)is difficult.However,the outcomes of CCE are uncertain.AIM To investigate the outcomes of Japanese patients with negative findings(no polyps or colorectal cancer)on initial CCE.METHODS This retrospective,single-center study was conducted at the Endoscopic Center at Aishinkai Nakae Hospital.This study included patients who underwent continuous CCE between November 2013 and August 2019,that exhibited no evidence of polyps or colorectal cancer at the initial CCE,and could be followed up using either the fecal immunochemical test(FIT),CS,or CCE.The observational period,follow-up method,presence or absence of polyps and colorectal cancer,pathological diagnosis,and number of colorectal cancer deaths were evaluated.RESULTS Thirty-one patients(mean age,60.4±15.6 years;range,28–84 years;14 men and 17 women)were enrolled in this study.The reasons for performing the first CCE were screening in 12,a positive FIT in six,lower abdominal pain in nine,diarrhea in two,and anemia in two patients.The mean total water volume at the time of examination was 3460±602 mL(2250–4800 mL),and a total CS was performed in 28 patients(90%).The degree of cleanliness was excellent in 15 patients and good in 16,and no poor cases were observed.No adverse events,such as retention or capsule aspiration,were observed in any of the patients.The mean follow-up period was 3.1±1.5 years(range,0.3–5.5 years).Follow-up included FIT in nine,CS in 20,and CCE in four patients(including duplicate patients).The FIT was positive in two patients,while CS revealed five polyp lesions(three in the ascending colon,one in the transverse colon,and one in the descending colon),with sizes ranging between 2 mm and 8 mm.Histopathological findings revealed a hyperplastic polyp in one patient,and adenoma with low grade dysplasia in four patients;colorectal cancers were not recognized.In the follow-up example by CCE,polyps and colorectal cancer could not be recognized.During the follow-up period,there were no deaths due to colorectal cancer in any of the patients.CONCLUSION We determined the outcomes in patients with negative initial CCE findings. 关键词：Colon capsule endoscopy Negative findings Observation Colorectal polyps Colorectal cancer Colorectal cancer death

相关文献

参考文献（15）
引证文献（1）
耦合文献（0）

参考文献(15)

引证文献(1)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Follow-up outcomes in patients with negative initial colon capsule endoscopy findings

参考文献(15)

引证文献(1)

用户提示