Association between mucosal surface pattern under near focus technology and Helicobacter pylori infection

查看全文 作　　者：Felipe [1]Fiuza;Fauze Maluf-[1]Filho;Edson [1]Ide;Carlos Kiyoshi Furuya [1]Jr;Sonia Nadia [1]Fylyk;Jennifer Nakamura [1]Ruas;Luciana [1]Stabach;Gabriela Albuquerque [1]Araujo;Sergio Eiji [1]Matuguma;Ricardo Sato [1]Uemura;Christiano Makoto [1]Sakai;Kendi [1]Yamazaki;Sergio Shiguetoshi [1]Ueda;Paulo [1]Sakai;Bruno Costa [1]Martins

机构地区：[1]Department of Endoscopy,Hospital Alemão Oswaldo Cruz,São Paulo 01323-020,Brazil

出　　处：《World Journal of Gastrointestinal Endoscopy》索引2021年第13卷第10期,共11页

摘　　要：BACKGROUND Many studies evaluated magnification endoscopy(ME)to correlate changes on the gastric mucosal surface with Helicobacter pylori(H.pylori)infection.However,few studies validated these concepts with high-definition endoscopy without ME.AIM To access the association between mucosal surface pattern under near focus technology and H.pylori infection status in a western population.METHODS Cross-sectional study including all patients referred to routine upper endoscopy.Endoscopic exams were performed using standard high definition(S-HD)followed by near focus(NF-HD)examination.Presence of erythema,erosion,atrophy,and nodularity were recorded during S-HD,and surface mucosal pattern was classified using NF-HD in the gastric body.Biopsies were taken for rapid urease test and histology.RESULTS One hundred and eighty-seven patients were analyzed from August to November 2019.Of those,47(25.1%)were H.pylori+,and 42(22.5%)had a previous H.pylori treatment.In the examination with S-HD,erythema had the best sensitivity for H.pylori detection(80.9%).Exudate(99.3%),nodularity(97.1%),and atrophy(95.7%)demonstrated better specificity values,but with low sensitivity(6.4%-19.1%).On the other hand,the absence of erythema was strongly associated with H.pylori-(negative predictive value=92%).With NF-HD,56.2%of patients presented type 1 pattern(regular arrangement of collecting venules,RAC),and only 5.7%of RAC+patients were H.pylori+.The loss of RAC presented 87.2%sensitivity for H.pylori detection,70.7%specificity,50%positive predictive value,and 94.3%negative predictive value,indicating that loss of RAC was suboptimal to confirm H.pylori infection,but when RAC was seen,H.pylori infection was unlikely.CONCLUSION The presence of RAC at the NF-HD exam and the absence of erythema at S-HD were highly predictive of H.pylori negative status.On the other hand,the loss of RAC had a suboptimal correlation with the presence of H.pylori. 关键词：Diagnosis ENDOSCOPY Gastric infection GASTRITIS Helicobacter pylori Sensitivity and specificity

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Association between mucosal surface pattern under near focus technology and Helicobacter pylori infection

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