Exosome-Coated Zeolitic Imidazolate Framework Nanoparticles for Intracellular Detection of ATP

查看全文 作　　者：Wenxing [1,2]Lv;Ziwei [2,3]Han;Yike [2,3]Li;Yanjuan [2,3]Huang;Jiashu [2,3]Sun;Xiaoquan [1,4]Lu;Chao [2,3]Liu

机构地区：[1]Tianjin Key Laboratory of Molecular Optoelectronic Sciences,Department of Chemistry,School of Science,Tianjin University,Tianjin 300072,China;[2]Beijing Engineering Research Center for BioNanotechnology,CAS Key Laboratory of Standardization and Measurement for Nanotechnology,CAS Center for Excellence in Nanoscience,National Center for Nanoscience and Technology,Beijing 100190,China;[3]School of Future Technology,University of Chinese Academy of Sciences,Beijing 100049,China;[4]Key Laboratory of Bioelectrochemistry and Environmental Analysis of Gansu Province,College of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou,Gansu 730070,China

出　　处：《Chinese Journal of Chemistry》索引2021年第39卷第8期,共6页

基　　金：This work was supported financially by the National Natural Science Foundation of China(Nos.22025402,91959101,and 21904028);Chinese Academy of Sciences(Nos.YJKYYQ20190068 and ZDBS-LY-SLH025);the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000). 摘　　要：The intracellular delivery of metal-organic frameworks(MOFs)encapsulated with functional biomolecules represents a promising av-enue in the field of biomedicine and biosensing.To improve the cellular uptake efficiency of MOFs,here we report the fabrication of cancer cell-derived exosome membra ne(EM)-coated zeolitic imidazolate framework-8(EM-ZIF-8)nan oparticles by using a microfluidic son ication device. 关键词：ATP EXOSOME Metal-organic frameworks MICROREACTORS Nan oparticles

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Exosome-Coated Zeolitic Imidazolate Framework Nanoparticles for Intracellular Detection of ATP

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