Non-surgical treatment of hilar cholangiocarcinoma

查看全文 作　　者：Riccardo [1]Inchingolo;Fabrizio [1]Acquafredda;Valentina [2]Ferraro;Letizia [3]Laera;Gianmarco [3]Surico;Alessia [4]Surgo;Alba [4]Fiorentino;Stefania [5]Marini;Nicola de'[6]Angelis;Riccardo [2]Memeo;Stavros [7]Spiliopoulos

机构地区：[1]Interventional Radiology Unit,'F.Miulli'General Regional Hospital,Acquaviva Delle Fonti 70124,Italy;[2]Unit of Hepato-Pancreatic-Biliary Surgery,'F.Miulli'General Regional Hospital,Acquaviva Delle Fonti 70021,Italy;[3]Department of Oncology,'F.Miulli'General Regional Hospital,Acquaviva Delle Fonti 70021,Italy;[4]Department of Radiation Oncology,'F.Miulli'General Regional Hospital,Acquaviva Delle Fonti 70021,Italy;[5]Department of Radiology,'F.Miulli'General Regional Hospital,Acquaviva Delle Fonti 70021,Italy;[6]Unit of Minimally Invasive and Robotic Digestive Surgery,'F.Miulli'General Regional Hospital,Acquaviva Delle Fonti 70021,Italy;[7]2^(nd) Department of Radiology,School of Medicine,National and Kapodistrian University of Athens,Athens 12461,Greece

出　　处：《World Journal of Gastrointestinal Oncology》索引2021年第13卷第11期,共13页

摘　　要：Cancer of the biliary confluence also known as hilar cholangiocarcinoma(HC)or Klatskin tumor,is a rare type of neoplastic disease constituting approximately 40%-60%of intrahepatic malignancies,and 2% of all cancers.The prognosis is extremely poor and the majority of Klatskin tumors are deemed unresectable upon diagnosis.Most patients with unresectable bile duct cancer die within the first year after diagnosis,due to hepatic failure,and/or infectious complications secondary to biliary obstruction.Curative treatments include surgical resection and liver transplantation in highly selected patients.Nevertheless,very few patients are eligible for surgery or transplant at the time of diagnosis.For patients with unresectable HC,radiotherapy,chemotherapy,photodynamic therapy,and liver-directed minimally invasive procedures such as percutaneous image-guided ablation and intra-arterial chemoembolization are recommended treatment options.This review focuses on currently available treatment options for unresectable HC and discusses future perspectives that could optimize outcomes. 关键词：CHOLANGIOCARCINOMA Interventional radiology ONCOLOGY LIVER RADIOTHERAPY Ablation

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Non-surgical treatment of hilar cholangiocarcinoma

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