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Highly responsive biosensors based on organic field-effect transistors under light irradiation

查看全文 作　　者：Xiaoqian [1]Jiang;Chenfang [1]Sun;Congcong [2]Zhang;Shanshan [1]Cheng 高影响力作者 机构地区：[1]Department of Chemistry,Tianjin Key Laboratory of Molecular Optoelectronic Sciences School of Science,Tianjin University,Tianjin 300072,China;[2]Institute for Advanced Interdisciplinary Research,University of Jinan,Ji'nan 250011,China高影响力机构 出　　处：《Chinese Chemical Letters》索引2021年第32卷第11期,共4页高影响力期刊 基　　金：financially supported by the Ministry of Science and Technology of China(Nos.2015CB856502,2016YFB0401100 and 2017YFA0204503);National Natural Science Foundation of China(Nos.21705116,51733004,91433115,51633006,51703160,21661132006,21473222 and 51902131). 摘　　要：High responsivity and sensitivity play essential roles in the development of organic field-effect transistors(OFETs)-based biosensors with regard to biological detections,particularly for disease diagnosis.Nonetheless,how to design a biosensor which improves these two outstanding properties while achieving low cost,easy processing,and time saving is a daunting challenge.Herein,a novel biosensor based on OFET with copolymer thin film,whose surface is illuminated with a suitable light beam is reported.This film can be used as both an organic semiconductor material and as a photoelectric active material.Due to amplification of signals as a result of the film’s strong response to light,the biosensor possesses higher responsivity and sensitivity compared to dark condition and even realizes a maximum responsivity of up to 10^(3)for alpha-fetoprotein(AFP)detection.The simple combination of light and transistor builds a bridge between photoelectric effect and biological system.In addition,the emergence of more excellent photoelectric active materials is expected to pave a way for ultrasensitive bio-chemical diagnostic tools. 关 键 词：Organic field-effect transistors Photoelectric active materials Photo response Biosensors Disease diagnosis
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