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Small bowel adenocarcinoma:An overview

查看全文 作  者:Divya [1]Khosla;Treshita [1]Dey;Renu [1]Madan;Rahul [2]Gupta;Shikha [1]Goyal;Narendra [1]Kumar;Rakesh [1]Kapoor 高影响力作者 机构地区:[1]Department of Radiotherapy and Oncology,Postgraduate Institute of Medical Education and Research,Chandigarh 160012,India;[2]Department of Gastroenterology,Shalby Multispeciality Hospital,Mohali 160062,Punjab,India高影响力机构 出  处:《World Journal of Gastrointestinal Oncology》索引2022年第14卷第2期,共10页高影响力期刊 摘  要:Small bowel adenocarcinoma(SBA)is a rare malignancy of the gastrointestinal tract.However,these tumors are among those with worst prognosis.Vague clinical signs and symptoms and radiological diagnostic challenges often delay treatment,which negatively impacts the prognosis of the patients.However,recent advances in imaging technology,like multidetector computed tomography,magnetic resonance imaging,and capsule endoscopy,have made earlier and accurate diagnosis possible.Surgery is the treatment of choice followed by adjuvant therapy.However,there are no strict treatment guidelines available for the management of SBA.Most of the available evidence from colorectal and gastric carcinoma has been extrapolated to adequately manage SBA.Prognosis for SBA is better than gastric carcinoma but worse than colorectal carcinoma.Currently,there is not enough information on the molecular characteristics and tumor pathogenesis.Because the incidence of SBA is very low,there is a need for further studies to evaluate the possible application of newer investigative agents and strategies to obtain a better outcome within the framework of international collaborations. 关 键 词:ADENOCARCINOMA CHEMOTHERAPY Prognostic factors Small bowel SURGERY
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