Neuroinflammation and subarachnoid hemorrhage: a revised look at the literature

查看全文 作　　者：Sai [1]Sriram;Christopher [2]Cutler;Mohammed [3]Azab;Ramya [1]Reddy;Rodeania [1]Peart;Brandon Lucke-[1]Wold

机构地区：[1]Department of Neurosurgery,University of Florida,Gainesville,FL,U.S.A.;[2]Rosalind Franklin University of Medicine and Science,Chicago,IL,U.S.A.;[3]Department of Biomolecular Sciences,Boise State University,Boise,ID,U.S.A.

出　　处：《Clinical Research Communications》索引2022年第5卷第3期,共11页

摘　　要：A key topic for aneurysmal subarachnoid hemorrhage is neuroinflammation.Neuroinflammation can predispose to aneurysm formation and rupture.Neuroinflammation can also result from the blood breakdown products after aneurysm rupture.Recent evidence has shown that perpetual neuroinflammation can contribute to vasospasm and hydrocephalus.Targeting neuroinflammation is a novel mechanism for preventing subsequent neurologic sequalae.In this review,we highlight the pathophysiology of aneurysm formation,the neuroinflammatory surge after rupture including the involved cytokines,and ultimately tie in the contributory clinical relevance.In the last sections,we look at the pre-clinical data and novel avenues for further discovery.This paper will be a useful resource to both the clinician and scientific investigator. 关键词：NEUROINFLAMMATION subarachnoid hemorrhage treatment approach aneurysm formation

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Neuroinflammation and subarachnoid hemorrhage: a revised look at the literature

参考文献(132)

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耦合文献(19)

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