Microorganism-derived biological macromolecules for tissue engineering

查看全文 作　　者：Naser [1,2]Amini;Peiman Brouki [1,2,3]Milan;Vahid Hosseinpour [1,2]Sarmadi;Bahareh [2]Derakhshanmehr;Ahmad [1,4]Hivechi;Fateme [5]Khodaei;Masoud [6]Hamidi;Sara [7]Ashraf;Ghazaleh [7]Larijani;Alireza [8,9]Rezapour

机构地区：[1]Cellular and Molecular Research Center,Iran University of Medical Sciences,Tehran 1591639675,Iran;[2]Institutes of Regenerative Medicine,Faculty of Advanced Technologies in Medicine,Iran University of Medical Sciences,Tehran 1449614535,Iran;[3]Department of Tissue Engineering and Regenerative Medicine,Faculty of Advanced Technologies in Medicine,Iran University of Medical Sciences,Tehran 1449614535,Iran;[4]Department of Pharmaceutics,University of Minnesota,MN 55455,USA;[5]Burn Research Center,Department of Plastic and Reconstructive Surgery,Iran University of Medical Sciences,Tehran 1591639675,Iran;[6]Department of Medical Biotechnology,Faculty of Paramedicine,Guilan University of Medical Sciences,Rasht 4477166595,Iran;[7]Department of Biology,Science and Research Branch,Islamic Azad University,Tehran 1477893855,Iran;[8]Cellular and Molecular Research Centre,Qom University of Medical Sciences,Qom 3715835155,Iran;[9]Department of Tissue Engineering and Regenerative Medicine,School of Medicine,Qom University of Medical Sciences,Qom 3715835155,Iran

出　　处：《Frontiers of Medicine》索引2022年第16卷第3期,共20页

摘　　要：According to literature,certain microorganism productions mediate biological effects.However,their beneficial characteristics remain unclear.Nowadays,scientists concentrate on obtaining natural materials from live creatures as new sources to produce innovative smart biomaterials for increasing tissue reconstruction in tissue engineering and regenerative medicine.The present review aims to introduce microorganism-derived biological macromolecules,such as pullulan,alginate,dextran,curdlan,and hyaluronic acid,and their available sources for tissue engineering.Growing evidence indicates that these materials can be used as biological material in scaffolds to enhance regeneration in damaged tissues and contribute to cosmetic and dermatological applications.These natural-based materials are attractive in pharmaceutical,regenerative medicine,and biomedical applications.This study provides a detailed overview of natural-based biomaterials,their chemical and physical properties,and new directions for future research and therapeutic applications. 关键词：biological macromolecules regenerative medicine tissue engineering EXOPOLYSACCHARIDE CARBOHYDRATE

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Microorganism-derived biological macromolecules for tissue engineering

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