Double tracer PET/CT:what is it and what does it mean?

查看全文 作　　者：Mattia [1]Pellicciari;Silvia [1]Ortolani;Elisabetta [1]Grego;Giampaolo [1]Tortora;Sara [1]Cingarlini 机构地区：[1]Department of Clinical Oncology,Comprehensive Cancer Network,G.B.Rossi University Hospital,University of Verona,37134 Verona,Italy 出　　处：《Journal of Cancer Metastasis and Treatment》索引2016年第2卷第1期,共8页 摘　　要：^(68)Ga-DOTA-peptide PET/CT is a recommended imaging modality in the workup of neuroendocrine neoplasms(NENs),which shows high diagnostic sensitivity and is a strong predictor of successful somatostatin receptor directed treatments.Although not routinely recommended,reliable evidences show that^(18)F-FDG PET/CT can provide complementary information in this setting with the ability to discriminate slow-proliferating tumors from aggressive,rapidly-proliferating tumors.Further,it has been proposed as an independent prognostic factor for the prediction of either overall survival or progression free survival.In this review,we provide insight into the biologic significance of ^(68)Ga-DOTA-peptides and ^(18)F-FDG uptake,and of the use of double tracer(^(68)Ga-DOTA-peptides plus ^(18)F-FDG)PET/CT in the clinical evaluation of patients affected by NENs. 关 键 词：68Ga-DOTATOC PET/CT ^(18)F-FDG PET/CT neuroendocrine neoplasms