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Olfactory and gustatory dysfunctions of COVID-19 patients in China:A multicenter study

查看全文 作　　者：Jianhui [1,2,3,4]Li;Yi [5]Sun;Enqiang [6,7]Qin;Hu [1,2,5]Yuan;Mingbo [1,2,3,4]Liu;Wenqi [1,2]Yi;Zhu [6,7]Chen;Chengcheng [5]Huang;Fengjie [5]Zhou;Ruiyao [5]Chen;Leibo [5]Zhang;Ning [1,2]Yu;Qiong [1,2]Liu;Xuejun [1,2]Zhou;Jingjing [1,2]He;Boyu [1,2]Li;Fusheng [6,7]Wang;Changliang [5]Yang;Shiming [1,2]Yang 高影响力作者 机构地区：[1]College of Otolaryngology Head and Neck Surgery,Chinese PLA General Hospital,Beijing,China;[2]National Clinical Research Center for Otolaryngologic Diseases,Beijing,China;[3]Department of Otolaryngology Head and Neck Surgery,Chinese PLA General Hospital Hainan Hospital,Sanya,China;[4]Hainan Clinical Research Center for Otolaryngologic Diseases,Sanya,China;[5]Department of Otolaryngology Head and Neck Surgery,General Hospital of Central Theater Command,Wuhan,China;[6]Treatment and Research Center for Infectious Diseases,The Fifth Medical Center of Chinese PLA General Hospital,Beijing,China;[7]National Clinical Research Center for Infectious Diseases,Beijing,China高影响力机构 出　　处：《World Journal of Otorhinolaryngology-Head and Neck Surgery》索引2022年第8卷第4期,共5页高影响力期刊 摘　　要：Introduction:With the spread of the epidemic worldwide,an increasing number of doctors abroad have observed the following atypical symptoms of coronavirus disease 2019(COVID-19):olfactory or taste disorders.Therefore,clarifying the incidence and clinical characteristics of olfactory and taste disorders in Chinese COVID-19 patients is of great significance and urgency.Materials and Methods:A retrospective study was conducted,which included 229 severe acute respiratory syndrome coronavirus 2 confirmed patients,through face-to-face interviews and telephone follow-up.Following the completion of questionnaires,the patients participating in the study,were categorized according to the degree of olfactory and taste disorders experienced,and the proportion of each clinical type of patient with olfactory and taste disorders and the time when symptoms appeared were recorded.Results:Among the 229 patients,31(13.54%)had olfactory dysfunction,and 44(19.21%)had gustatory dysfunction.For the patients with olfactory dysfunction,6(19.35%)developed severe disease and became critically ill.Olfactory dysfunction appeared before the other symptoms in 21.43%of cases.The proportion of females with olfactory and gustatory dysfunction was higher than that of males(P<0.001).Conclusions:The incidence of olfactory and gustatory dysfunction was much lower than that reported abroad;the prognosis of patients with olfactory dysfunction is relatively favorable;olfactory and gustatory dysfunction can be used as a sign for early screening;females are more prone to olfactory and gustatory dysfunction. 关 键 词：COVID-19 GUSTATORY OLFACTORY SARS-CoV-2
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